Salud Mental

Prevalence and factors associated with depressive symptoms in individuals living with HIV/AIDS

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Renata Karina Reis
Elizabete Santos Melo
Carolina de Castro Castrighini
Marli Terezinha Gimeniz Galvão
Silmara Elaine Toffano-Malaguti
Elucir Gir

Abstract

Introduction. Symptoms of depression are highly prevalent among people living with HIV/AIDS in Brazil and in other countries. This situation points to the need for proper diagnosis and timely treatment by the health team.

Objective. To identify the prevalence of depressive symptoms and its association with sociodemographic, clinical and behavioral disorders among PLWHA.

Method. This cross-sectional study analyzed 331 people living with HIV/AIDS in the city of São Paulo, Southeast Brazil. The Beck Depression Inventory was used to assess depressive symptoms. To identify predictors of depression, a multiple regression model was used, with a 95% confidence interval.

Results. Of the participants, 167 (50.5%) were men, with an average age of 40. Depressive symptoms were prevalent in 42.3% and the factors associated with depression were being employed, age, and immunological status. Being employed was 1.8 times more likely (95% CI [1.0, 2.8]) to develop depressive symptoms than those who were not employed. The odds ratio of individuals under the age of 40 indicates they were 1.8 times more likely (95% CI [1.1, 2.8]) to have depressive symptoms than those over 40 years old. In regard to clinical aspects, individuals with 200 CD4 cells per mm3 are 2.1 times (95% CI [1.1, 3.9]) more likely to develop depression.

Discussion and conclusion. We conclude that the prevalence of depressive symptoms among people living with HIV/AIDS was 42.3% and it was associated with being employed, age and CD4 + cell count.

Keywords:
depression, HIV, mental health, public health

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References

Sales Da Silva LM, Aparecida M, Moura V, Lucia M, Pereira D. Cotidiano de mulheres após contágio pelo hiv/aids: subsídios norteadores da assistência de enfermagem 1. Abr-Jun. 2013;22(2):335–42.

Reis RK, Haas VJ, Santos CB dos, Teles SA, Galvão MTG, Gir E. Symptoms of depression and quality of life of people living with HIV/AIDS. Rev Lat Am Enfermagem [Internet]. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo; 2011 Aug [cited 2016 Sep 18];19(4):874–81. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-11692011000400004&lng=en&nrm=iso&tlng=em

Brasil. Ministério da Saúde. Departamento de DST, Aids e Hepatites Virais, Secretaria de Vigilância em Saúde. Atenção em Saúde Mental nos Serviços Especializados em DST/Aids. Brasília-DF, 2012. Available from: http://bvsms.saude.gov.br/bvs/publicacoes/atencao_saude_mental_servicos_dst.pdf

Silveira MPT, Guttier MC, Pinheiro CAT, Pereira TVS, Cruzeiro ALS, Moreira LB. Depressive symptoms in HIV-infected patients treated with highly active antiretroviral therapy. Rev Bras Psiquiatr [Internet]. Associação Brasileira de Psiquiatria (ABP); 2012 Jun [cited 2016 Sep 18];34(2):162–7. Available from: http://linkinghub.elsevier.com/retrieve/pii/S151644461270034X

Israelski DM, Prentiss DE, Lubega S, Balmas G, Garcia P, Muhammad M, et al. Psychiatric co-morbidity in vulnerable populations receiving primary care for HIV/AIDS. AIDS Care [Internet]. Taylor & Francis Group ; 2007 Feb 11 [cited 2016 Sep 18];19(2):220–5. Available from: http://www.tandfonline.com/doi/full/10.1080/09540120600774230

Sherr L, Clucas C, Harding R, Sibley E, Catalan J. HIV and depression--a systematic review of interventions. Psychol Health Med [Internet]. 2011 Oct [cited 2016 Sep 18];16(5):493–527. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21809936

World Health Organization. Depression 2010. [Internet]. [Access 05 December 2015]. Available from: http://www.who.int/topics/depression/en/

Andrade L, Gorenstein C, Vieira Filho AH, Tung TC, Artes R. Psychometric properties of the Portuguese version of the State-Trait Anxiety Inventory applied to college students: factor analysis and relation to the Beck Depression Inventory. Brazilian J Med Biol Res [Internet]. Brazilian Journal of Medical and Biological Research; 2001 Mar [cited 2016 Sep 18];34(3):367–74. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300011&lng=en&nrm=iso&tlng=en

Paula JM de, Sonobe HM, Nicolussi AC, Zago MMF, Sawada NO. Symptoms of depression in patients with cancer of the head and neck undergoing radiotherapy treatment: a prospective study. Rev Lat Am Enfermagem [Internet]. [cited 2016 Sep 18];20(2):362–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22699738

Dal-Bó MJ, Manoel AL, Filho AOB, Silva BQT da, Cardoso YS, Cortez J, et al. Depressive Symptoms and Associated Factors among People Living with HIV/AIDS. J Int Assoc Provid AIDS Care [Internet]. SAGE Publications; 2015 [cited 2016 Sep 18];14(2):136–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23873218

Mello VA de, Malbergier A. Depression in women infected with HIV. Rev Bras Psiquiatr [Internet]. Associação Brasileira de Psiquiatria (ABP); 2006 Mar [cited 2016 Sep 18];28(1):10–7. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462006000100004&lng=en&nrm=iso&tlng=en

Schimitt JHL, Silva RM. Prevalence of depressive symptoms in patients with HIV/AIDS in a referral hospital in the city of Florianóplois-SC. ACM Arq. Catarin. Med 2009; 38(2):90-97. Available from: http://www.acm.org.br/revista/

Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry [Internet]. 2001 May [cited 2016 Sep 18];158(5):725–30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11329393

Teng CT, Humes E de C, Demetrio FN. Depressão e comorbidades clínicas. Rev Psiquiatr Clínica [Internet]. Faculdade de Medicina da Universidade de São Paulo; 2005 Jun [cited 2016 Sep 18];32(3):149–59. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-60832005000300007&lng=pt&nrm=iso&tlng=pt

Malbergier A, Schöffel AC. Tratamento de depressão em indivíduos infectados pelo HIV. Rev Bras Psiquiatr [Internet]. Associação Brasileira de Psiquiatria (ABP); 2001 Sep [cited 2016 Sep 18];23(3):160–7. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462001000300009&lng=pt&nrm=iso&tlng=pt

Mello VA, Segurado AA, Malbergier A. Depression in women living with HIV: clinical and psychosocial correlates. Arch Womens Ment Health [Internet]. 2010 Jun [cited 2016 Sep 18];13(3):193–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19760048

Barros MB de A, Francisco PMSB, Zanchetta LM, César CLG. Tendências das desigualdades sociais e demográficas na prevalência de doenças crônicas no Brasil, PNAD: 2003- 2008. Cien Saude Colet [Internet]. ABRASCO - Associação Brasileira de Saúde Coletiva; 2011 Sep [cited 2016 Sep 18];16(9):3755–68. Available from: http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1413-81232011001000012&lng=pt&nrm=iso&tlng=pt

Bromet E, Andrade LH, Hwang I, Sampson NA, Alonso J, de Girolamo G, et al. Cross-national epidemiology of DSM-IV major depressive episode. BMC Med [Internet]. BioMed Central; 2011 Dec 26 [cited 2016 Sep 18];9(1):90. Available from: http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-9-90

Viana MC, Andrade LH. Lifetime Prevalence, Age and Gender Distribution and Age-of-Onset of Psychiatric Disorders in the São Paulo Metropolitan Area, Brazil: Results from the São Paulo Megacity Mental Health Survey. Rev Bras Psiquiatr [Internet]. Associação Brasileira de Psiquiatria (ABP); 2012 Sep [cited 2016 Sep 18];34(3):249–60. Available from: http://linkinghub.elsevier.com/retrieve/pii/S1516444612000037

Santos W, Bouttelet D, Ii M, Medeiros Iii M. O grupo de mulheres que vivem e convivem com HIV/AIDS: um relato de experiência The women’s group that lives and coexist with HIV/AIDS: a report of experience El grupo de las mujeres que viven y conviven cón VIH/SIDA: un relato de experiencia. Eletr Enf [Internet] [Internet]. 1043 [cited 2016 Sep 18];11(4). Available from: http://www.fen.ufg.br/revista/v11/n4/v11n4a32.htm.

Carvalho CM de L, Galvão MTG. Enfrentamento da AIDS entre mulheres infectadas em Fortaleza - CE. Rev da Esc Enferm da USP [Internet]. Revista da Escola de Enfermagem da USP; 2008 Mar [cited 2016 Sep 18];42(1):90–7. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342008000100012&lng=pt&nrm=iso&tlng=pt

Rodkjaer L, Laursen T, Balle N, Sodemann M. Depression in patients with HIV is under-diagnosed: a cross-sectional study in Denmark. HIV Med [Internet]. 2010 Jan [cited 2016 Sep 18];11(1):46–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19601996

Santos, Anderson Moreira Aristides; Jacinto, Paulo de Andrade ; Tejada CAO. Causalidade entre renda e saúde: uma análise através da abordagem de dados em painel com os estados do Brasil. Est Econ. 2012;42(2):229–61.

Rueda S, Raboud J, Mustard C, Bayoumi A, Lavis JN, Rourke SB. Employment status is associated with both physical and mental health quality of life in people living with HIV. AIDS Care [Internet]. Taylor & Francis Group ; 2011 Apr [cited 2016 Sep 18];23(4):435–43. Available from: http://www.tandfonline.com/doi/abs/10.1080/09540121.2010.507952

Kaharuza FM, Bunnell R, Moss S, Purcell DW, Bikaako-Kajura W, Wamai N, et al. Depression and CD4 cell count among persons with HIV infection in Uganda. AIDS Behav [Internet]. 2006 Jul [cited 2016 Sep 18];10(4 Suppl):S105–11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16802195

Silveira Leite V, Motta DD, Spack M, Araujo SM, Pupulin ART. Depressão, estresse e alexitimia em pacientes com infecção pelo vírus HIV. Acta Sci - Heal Sci. 2007;

Pence BW, Miller WC, Gaynes BN, Eron JJ. Psychiatric illness and virologic response in patients initiating highly active antiretroviral therapy. J Acquir Immune Defic Syndr [Internet]. 2007 Feb 1 [cited 2016 Sep 18];44(2):159–66. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17146374

Primeau MM, Avellaneda V, Musselman D, St Jean G, Illa L. Treatment of depression in individuals living with HIV/AIDS. Psychosomatics [Internet]. [cited 2016 Sep 18];54(4):336–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23380671

Sarni ROS, Souza FIS de, Battistini TRB, Pitta TS, Fernandes AP, Tardini PC, et al. Lipodystrophy in children and adolescents with acquired immunodeficiency syndrome and its relationship with the antiretroviral therapy employed. J Pediatr (Rio J) [Internet]. [cited 2016 Sep 18];85(4):329–34. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19668909

Samet JH, Horton NJ, Meli S, Freedberg KA, Palepu A. Alcohol consumption and antiretroviral adherence among HIV-infected persons with alcohol problems. Alcohol Clin Exp Res [Internet]. 2004 Apr [cited 2016 Sep 18];28(4):572–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15100608

Sullivan LE, Saitz R, Cheng DM, Libman H, Nunes D, Samet JH. The impact of alcohol use on depressive symptoms in human immunodeficiency virus-infected patients. Addiction [Internet]. NIH Public Access; 2008 Sep [cited 2016 Sep 18];103(9):1461–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18637000

Brasil. Ministério da Saúde. Departamento de DST, Aids e Hepatites Virais, Secretaria de Vigilância em Saúde. Avaliação da qualidade dos serviços ambulatoriais do SUS que assistem adultos vivendo com o HIV/Aids no Brasil, Brasília-DF, 2011. Available from: http://www.aids.gov.br/sites/default/files/anexos/publicacao/2012/52013/relat_rio_final_qualiaids_2010_11614.pdf.

Pyne JM, Fortney JC, Curran GM, Tripathi S, Atkinson JH, Kilbourne AM, et al. Effectiveness of collaborative care for depression in human immunodeficiency virus clinics. Arch Intern Med [Internet]. 2011 Jan 10 [cited 2016 Sep 18];171(1):23–31. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21220657